Platelet-Derived Growth Factor (PDGF) is one of the body’s most powerful natural signals for healing and regeneration. It stimulates collagen production, boosts skin cell turnover, promotes new blood vessel growth, and supports tissue repair. Already FDA-approved for wound and bone healing, PDGF is now being utilized in aesthetics for its potential to rejuvenate and restore skin—applying proven science to beauty.
Ariessence Pure PDGF+ is an exciting new advancement in regenerative aesthetics, designed to enhance skin recovery and results. This topical serum features a pharmaceutical-grade, lab-engineered form of PDGF-BB—one of the most active and well-researched growth factors involved in tissue repair. Paired with hydrating hyaluronic acid, it’s typically applied after treatments like microneedling, radiofrequency, or fractional laser to support healing, reduce inflammation, and boost collagen production.
Unlike PRP or exosomes, which can vary in potency depending on individual health factors, Ariessence delivers a consistent, concentrated dose of PDGF-BB every time—offering a more controlled and predictable option for post-procedure care.
While its primary use is topical, there’s growing professional interest in its potential injectable applications—a promising area still under early exploration. As research continues, Ariessence PDGF+ stands at the forefront of a new era in aesthetic science, combining precision, potency, and innovation.
Platelet-derived growth factor
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PDGF is a natural protein your body produces to help heal and regenerate tissue. In hair restoration, it’s used to help revive dormant hair follicles, improve scalp health, and support stronger, healthier hair growth.
TREATMENT PLAN $4,800
-3 Treatments, 4-6 Weeks Apart
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PDGF is a natural protein your body uses to heal and repair itself. When used in aesthetic medicine, PDGF can be injected just beneath the skin to help refresh and rejuvenate your appearance—especially in areas where the skin is thinning, dull, or showing early signs of aging.
PDGF is often used in delicate areas, where the skin is thinner and harder to treat with traditional fillers. It’s a great option if you're looking for a more subtle, regenerative approach to skin rejuvenation without adding volume or altering your natural features.
TREATMENT PLAN $1,600
-2 Treatments, 6-8 Weeks Apart
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PDGF is an injectable that improves skin quality in delicate areas like the under-eye region. The goal is to leverage PDGF’s powerful regenerative properties to address common concerns such as:
Thin or crepey skin
Fine lines and wrinkles
Mild volume loss
Dark circles caused by poor circulation or thinning skin
When injected, PDGF is believed to:
Stimulate collagen and elastin production
Promote angiogenesis (formation of new blood vessels), which may help brighten and revitalize the under-eye area
Recruit other reparative cells to support dermal remodeling
Enhance the healing response following laser, microneedling, or RF treatments
TREATMENT PLAN $1,600
-2 Treatments, 6-8 Weeks Apart
FAQ's of PDGF
What is PDGF?
PDGF stands for Platelet-Derived Growth Factor—a naturally occurring protein your body uses to heal and regenerate tissue. When you get injured, PDGF is one of the first signals your body sends to start the repair process. It stimulates collagen production, helps form new blood vessels, and activates the cells responsible for rebuilding skin and tissue.
How is PDGF used in aesthetics?
In aesthetic medicine, PDGF is used to enhance skin quality, support healing after procedures, and even promote hair growth. It’s most commonly applied topically after treatments that trigger the skin’s repair response—like microneedling, radiofrequency, or laser resurfacing.
There is also growing interest in injectable PDGF, especially in areas like the under eyes and scalp, to directly stimulate collagen production and tissue regeneration. These uses are still emerging, but early results are promising.
What is Ariessence Pure PDGF+?
Ariessence Pure PDGF+ is a topical serum designed specifically for aesthetic use. It contains a pharmaceutical-grade, lab-engineered version of PDGF-BB, the most active and well-researched form of PDGF. It’s paired with hyaluronic acid to support hydration and comfort, and is typically applied after treatments that engage the skin’s natural healing process.
Unlike PRP (platelet-rich plasma), which varies from person to person, Ariessence delivers a consistent, high-concentration dose of PDGF every time—making it more predictable and often more potent.
What can PDGF do for my skin?
PDGF supports the skin from within by:
Stimulating collagen and elastin for firmer, smoother skin
Improving skin tone and texture
Enhancing healing after procedures
Reducing inflammation and redness
Promoting stronger, healthier skin structure over time
It’s especially helpful in delicate areas like the under eyes, where traditional fillers may not be appropriate, and where the goal is to strengthen and refresh—not add volume.
How are PDGF injections used under the eyes?
In emerging off-label uses, PDGF is injected in small amounts beneath the skin using a fine needle. The goal is to strengthen thin skin, reduce fine lines, and improve texture without changing facial volume. It helps support tissue regeneration by boosting collagen production and circulation in this sensitive area.
This treatment is not yet FDA-approved for injection, but early clinical use and case studies are showing positive results.
Can PDGF help with hair loss?
Yes! It can be injected into the scalp to:
Stimulate dormant hair follicles
Improve blood flow and scalp health
Support stronger, thicker hair growth
Enhance healing after hair procedures
Compared to PRP, PDGF offers precise dosing and doesn’t rely on drawing and processing your blood, making it a more controlled alternative.
Is PDGF safe?
Yes. PDGF has been extensively studied in medicine and is FDA-approved for use in wound healing, bone repair, and soft tissue regeneration. Its aesthetic uses are newer, but it has a strong safety profile and is already used in millions of medical treatments worldwide. When used topically, the risk is very low. Injectable use is still being monitored and studied for long-term safety and efficacy.
Who is a good candidate for PDGF treatments?
You may be a good candidate if you:
Want to improve skin texture, firmness, or tone
Are looking to boost healing after microneedling, RF, or laser
Have thinning or crepey skin under the eyes
Are experiencing early signs of hair thinning or hair loss
Prefer a natural, regenerative approach over fillers or surgery
When will I see results?
PDGF works by supporting your body’s own healing and regeneration, so results develop gradually. Most patients start to notice improvements in skin quality within a few weeks, with continued results over 1–3 months. A series of treatments is recommended for best outcomes.
What makes PDGF different from PRP or exosomes?
PRP (Platelet-Rich Plasma) uses your own blood to extract growth factors, but results can vary based on your health, age, hydration, and more.
Exosomes are cellular messengers with promising potential but are still under regulatory review.
PDGF, especially in a product like Ariessence, is precisely engineered, sterile, and delivers a consistent, high-concentration dose every time—no blood draw needed.